Zlatanova J Molecular Biology Structure Dynamics of Genomes Proteomes 2ed 2023

Textbook in PDF format

Molecular Biology: Structure and Dynamics of Genomes and Proteomes second edition illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous, yet still concise, summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system, Coronaviruses – structure, genome, vaccine and drug development, and newly recognized mechanisms for transcription termination. The text is written for advanced undergraduate or graduate-level courses in molecular biology.
Key Features
Highlights the experimental basis of important discoveries in molecular biology
Thoroughly updated with new information on gene editing tools, viruses, and transcription mechanisms, termination and antisense
Provides learning objectives for each chapter
Includes a list of relevant videos from the Internet about the topics covered in the chapter
To the Cell and Beyond: The Realm of Molecular Biology.
From Classical Genetics to Molecular Genetics.
Proteins.
Nucleic Acids.
Recombinant DNA: Principles and Applications.
Protein-Nucleic Acid Interactions.
The Genetic Code, Genes, and Genomes.
Physical Structure of the Genomic Material.
Transcription in Bacteria.
Transcription in Eukaryotes.
Regulation of Transcription in Bacteria.
Regulation of Transcription in Eukaryotes.
Transcription Regulation in the Human Genome.
RNA Processing.
Translation: The Players.
Translation: The Process.
Regulation of Translation.
Protein Processing and Modification.
DNA Replication in Bacteria.
DNA Replication in Eukaryotes.
DNA Recombination.
DNA Repair. Glossary